What happens when the novel coronavirus enters the human respiratory tract? How does lung cell infection affect the immune response of the human body? Recently, American scientists recently published research results on related issues in Nature’s Newsletter, which is expected to provide new ideas for improving treatment strategies for coronavirus patients.
Researchers at Massachusetts General Hospital’ autopsy materials of 24 patients who died of COVID-19 found that there were two stages of infection in severe cases of COVID-19: in the early stage The amount of virus in the patient’s lungs is very large, which stimulates the immune response of the human body.
In the later stage, there is no virus in human tissues, but the damage caused by the virus to the lungs is too serious to recover.
David t., one of the researchers who carried out this study and deputy director of clinical innovation at the Massachusetts Comprehensive Cancer Center and assistant professor of medicine at Harvard Medical School.
Ting said that the research data also showed that the immune system can attack COVID-19, but the response varies from person to person, and even the same patient may respond differently from part to different parts of the lung, which also makes it difficult to treat “one drug for all”.
David also pointed out that drugs such as remdesivir are only effective in the early stage of infection.
The researchers also found that the coronavirus replicates very little in the human lungs, indicating that the virus mainly replicates in the nasal cavity and then enters the lungs, resulting in pneumonia and other complications.